Chapter eight brown adipose tissue in humans detection and functional analysis using pet positron emission tomography mri magnetic resonance imaging and dect dual energy computed tomography. Keywords medicine issue 96 magnetic resonance imaging brown adipose tissue cold activation adult human fat water imaging fluorodeoxyglucose positron emission tomography computed tomography because of these challenges reliable spatial mapping techniques that can distinguish bat from wat . The method presented here uses 18 f fluorodeoxyglucose 18 f fdg positron emission tomography computed tomography pet ct and fat water separated magnetic resonance imaging mri each scanned following 2 hr exposure to thermoneutral 24 c and cold conditions 17 c in order to map brown adipose tissue bat in adult human subjects. Abstract purpose to implement quantitative dixon magnetic resonance imaging mri methods for brown adipose tissue bat characterization at inactive and cold activated states in normal weight overweight and obese subjects. Characterisation and identification of brown adipose tissue on positron emission tomography and magnetic resonance imaging since the first published description of brown adipose tissue bat in 1551 its reputation has changed from that of a mere curiosity of little physiological significance in adult humans to meriting reclassification as a metabolic organ in its own right
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